KMID : 1145520170030020113
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Journal of Radiopharmaceuticals and Molecular Probes 2017 Volume.3 No. 2 p.113 ~ p.115
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A novel 11CN-labeling approach to aryl compounds and peptides using palladium complex
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Kim Hee-Kwon
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Abstract
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Since the nitrile group is commonly found in natural products and bioactive molecules, many scientists¡¯ interest has been focused on the usage of nitrile group. Novel reactions for 11C-labelling using nitrile group have been developed, and novel preparation protocols of biomolecules labeled with 11C have been studied. In this highlight review, recent researches for the novel labeling reactions using nitrile group are illustrated.
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KEYWORD
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Nitrile group, Palladium, C-11, Positron emission tomography (PET), Peptide
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